Minimum acceptable diet in a cohort of children aged between 6 and 15 months: Complementary feeding assessment and associated factors in the Brazilian western Amazon.

OBJECTIVE: The goal of the article was to assess complementary feeding patterns, and associated factors, of children between 6 and 15-month old in Rio Branco-Acre, Brazil, based on the minimum acceptable diet indicator. METHODS: This study was cross-sectional, including 857 children between ages 6 and 15 mo, from a 2015 birth cohort of Rio Branco, Brazil. The prevalence of complementary feeding indicators, minimum meal frequency, minimum dietary diversity, and minimum acceptable diet was estimated based on the recommendations of the World Health Organization. Sociodemographic characteristics, infant and maternal habits, prenatal information, birth characteristics, breastfeeding, and complementary feeding were evaluated. Differences between the proportions were evaluated by the χ2 test and univariate and multiple logistic regression analyses, to determine associated factors with child minimum acceptable diet. RESULTS: The minimum frequencies of meals and dietary diversity were observed in 81.0% and 51.8% of the children, respectively. The minimum acceptable diet prevalence was 47.1%. Also, minimum acceptable diet was inversely associated with C, D, and E social classes (adjusted odds ratio = 0.49; 95% CI, 0.33-0.72), number of living siblings (adjusted odds ratio for two or three children = 0.69; 95% CI, 0.48-0.98, and adjusted odds ratio for ≥ 4 children = 0.56; 95% CI, 0.37-0.84). Maternal regular consumption of fruits, vegetables, and legumes (adjusted odds ratio = 2.62; 95% CI, 1.69-4.05), child age from 12 to 15 mo (adjusted odds ratio = 2.05; 95% CI, 1.32-3.18), and receiving guidance regarding complementary feeding during postnatal consultations (adjusted odds ratio = 1.38; 95% CI, 1.03-1.86) were directly associated with minimum acceptable diet. CONCLUSIONS: Fewer than 50% of the children received adequate food with adequate frequency and diversity. Low socioeconomic status and having ≥ 2 living siblings reduced the chance of minimum acceptable diet, whereas maternal healthy diet, child age (12-15 mo), and complementary feeding counseling during postnatal appointments increased the chance of minimum acceptable diet.

Diet quality and associated factors in Brazilian undergraduates during the COVID-19 pandemic.

Background: Diet quality is associated with psychobiological, psychological, biological, and physiological factors of individuals, and in the context of prolonged stress, such as the COVID-19 pandemic, it can lead to a worsening of the quality of food for undergraduates. This study aimed to analyze diet quality and associated factors in Brazilian undergraduates. Methods: Data were collected from 4,799 undergraduate students from all Brazilian regions, from August 2020 to February 2021. The online questionnaire contained socioeconomic variables, the ESQUADA scale to assess diet quality, self-referred changes in weight, the Brazilian food insecurity scale (EBIA), sleep assessment and the perceived stress scale. Unconditional multiple logistic regression analysis was performed to study variables associated with poor and very poor diet quality. Results: Most of participants presented a good diet quality (51.7%), while 9.8% had a poor or very poor diet quality and only 1.1% had an excellent diet quality. 58.2% of undergraduates reported to have an increase in weight during the pandemic and 74.3% of the students presented elevated stress during the pandemic. Logistic regressions showed students who gained weight during the pandemic presented the highest AOR = 1.56 (95% CI = 1.12-2.20) for poor or very poor diet quality. The elevated perceived stress was also associated with a higher AOR = 2.85 (95% CI = 1.71-4.74) for poor or very poor diet quality. Conclusion: Most of the studied undergraduates presented a good diet quality. Nevertheless, poor/very poor diet quality was associated with higher perceived stress and weight gain. Our study indicated that policies should beaimed at the socioeconomically most vulnerable undergraduates, those in a situation of food and nutritional insecurity, high perceived stress, and who gained weight during the pandemic.

Effect of prenatal care quality on the risk of low birth weight, preterm birth and vertical transmission of HIV, syphilis, and hepatitis.

BACKGROUND: Averse birth-outcomes still affect newborns worldwide. Although high-quality prenatal care is the main strategy to prevent these outcomes, the effect of prenatal care based on Kotelchuck index combined with consultation contents is still unclear. Thus, this article to evaluate the effect of the quality of prenatal care (PC) process on birth indicators in a cohort of puerperaes who attended maternity hospitals in Brazilian western Amazon, city of Rio Branco, in the state of Acre, Brazil, in 2015. METHODS: This research was a hospital-based cohort study. The sample consisted of 1,030 women who gave birth in maternity hospitals in the city between April 6 and June 30, 2015. This research was a hospital-based cohort study. The sample consisted of 1,030 women who gave birth in maternity hospitals in Rio Branco between April 6th. and June 30th., 2015. Prenatal care was classified as fully adequate when started ≤4th month; ≥80.0-109% expected consultations for GA according to the Kotelchuck Index; ≥5 records of blood pressure, weight, GA, fundal height, ≥4 records of fetal heart rate, fetal movements or equivalent to 75% of the number of consultations; in addition to recording ABO/RH, hemoglobin, VDRL, urine, glucose, anti-HIV and anti-toxoplamosis during the 1st trimester. The evaluated outcomes were low birth weight (LBW), preterm birth and vertical transmission of human immunodeficiency virus (HIV)/hepatitis/syphilis. Differences between proportions were assessed using the X² test, and the crude and adjusted odds ratios (OR) (95% CI) were estimated using unconditional logistic regression. RESULTS: Overall cohort, the outcomes incidences were 8.8% for LBW, 9.2% for preterm birth, and 1.1% for vertical transmission (syphilis/HIV/hepatitis). Crude and adjusted OR showed that inadequate PC increased the risk statistically significant of LBW (ORcrude: 1.84; 95%CI: 0.99-3.44; ORadjusted: 1.87; 95%CI: 1.00-3.52), and preterm birth (ORcrude: 1.79; 95%CI: 1.00-3.29; ORadjusted: 3.98; 95%CI: 1.40-11.29). CONCLUSION: The results draw attention to the importance of quality PC in reducing the risks of LBW, preterm birth, and vertical transmission of syphilis/HIV/hepatitis. Moreover, using this proposed quality prenatal care indicator based on Kotelchuck index combined with consultations contents adjusted by GA may accurately predict unfavorable outcomes.

Prevalence of ultra-processed food, alcohol and tobacco consumption and chronic non-communicable diseases in Rio Branco, capital city of the state of Acre, Brazil, 2019: comparative analysis of two epidemiological surveys. / Prevalência de consumo de alimentos ultraprocessados, álcool, tabaco e doenças crônicas não transmissíveis em Rio Branco, Acre, 2019: análise comparativa de dois inquéritos epidemiológicos.

OBJECTIVE: To describe, in a comparative manner, the prevalence of chronic non-communicable diseases and ultra-processed food, alcohol and tobacco consumption, estimated by the Chronic Disease Risk and Protective Factors Surveillance Telephone Survey (Vigitel) and National Health Survey (PNS), in Rio Branco, capital city of the state of Acre, Brazil. METHODS: This was a cross-sectional study on sociodemographic, health and lifestyle data from surveys conducted in 2019. Prevalence and 95% confidence intervals (95%CI) were described, and percentage difference was calculated. RESULTS: Of the 3,037 individuals assessed, similar prevalence, with difference between Vigitel (60.3%; 95%CI 56.2;64.3) and PNS (70.8%; 95%CI 67.4;73.9) regarding people of Brown race/skin color was found. In the stratification by sex, it could be seen percentage difference between the surveys, regarding obesity (male= 6.5%; female= 0.4%), smoking (male= 4.0%; female= -1.5%) and alcohol abuse (male= 6.9%; female= -2.5%), although with overlapping 95%CI. CONCLUSION: The estimates assessed in both surveys were similar.

Factors Associated with Overweight and Obesity in Adults from Rio Branco, Acre in the Western Brazilian Amazon.

This study aimed to assess factors associated with overweight and obesity in adults from Rio Branco, Acre, in the western Brazilian Amazon. This is a cross-sectional, population-based study conducted in Rio Branco, which used data on individuals aged 18 years or older collected by the 2019 National Health Survey. Software R version 4.0.5 was used to estimate the prevalence of overweight and obesity, prevalence ratios, and 95% confidence intervals. Multiple analysis was performed by Poisson's regression with robust variance and hierarchical selection of variables. This study included 1217 adults. The prevalence of overweight was 58.2% (95%CI: 54.7-61.6) and of obesity, 20.1% (95%CI: 17.2-23.4). The factors associated with overweight were arterial hypertension (AdjPR: 1.45; 95%CI: 1.31-1.61), physical inactivity (AdjPR: 1.19; 95%CI: 1.04-1.36), age group (25-39 years, AdjPR: 1.49; 95%CI: 1.10-2.00; 40-59 years, AdjPR: 1.69; 95%CI: 1.28-2.23; 60 years or older, AdjPR: 1.37; 95%CI: 1.01-1.87); and smoking (AdjPR: 0.62; 95%CI: 0.41-0.93). The factors associated with obesity were arterial hypertension (AdjPR: 1.80; 95%CI: 1.41-2.30) and diabetes mellitus (AdjPR: 1.52; 95%CI: 1.08-2.13). Smoking and female sex remained in the hierarchical model for obesity, even without statistical significance. Despite intervention guidelines for these chronic diseases, there is a need for the public recognition of overweight and obesity and their possible associated factors in the Amazon and other regions with similar socioeconomic and demographic characteristics.

Time Trend of Overweight and Obesity in Adults from Rio Branco, Acre, Western Brazilian Amazon (2006-2020).

This study aimed to analyze overweight trend and obesity in adults from Rio Branco, Acre, Western Brazilian Amazon, from 2006 to 2020. This is a time series study, with data from Surveillance System for Risk and Protective Factors for Chronic Diseases by Telephone Survey (VIGITEL). To estimate annual percentage change (APC) and 95% confidence intervals, the software Jointpoint Regression Analysis v.4.6.0.0., was used. In Rio Branco, overweight prevalence ranged from 44.0% in 2006 to 58.9% in 2020, with a bigger frequency among men than that among women. Obesity prevalence has increased from 12.5% in 2006 to 21.4% in 2020, similar between both sexes. From 2006 to 2020, overweight APC was 5.2% (95% CI: 1.4; 9.1) by 2010, and decreased to 1.3% by 2020. Public policies to control obesity and its risks must be both, implemented as strengthened.

Prevalence of the consumption of ultra-processed foods, alcohol, tobacco and chronic non-communicable diseases in Rio Branco, Acre, Brazil, 2019: comparative analysis of two epidemiological surveys / Prevalencia del consumo de alimentos ultraprocesados, alcohol, tabaco y enfermedades crónicas no transmisibles en Rio Branco, Acre, Brasil, 2019: análisis comparativo de dos encuestas epidemiológicas / Prevalência de consumo de alimentos ultraprocessados, álcool, tabaco e doenças crônicas não transmissíveis em Rio Branco, Acre, 2019: análise comparativa de dois inquéritos epidemiológicos

Objective: To describe, comparatively, the prevalence of non-communicable chronic diseases, consumption of ultra-processed foods, alcohol and tobacco, estimated by the Surveillance System for Risk and Protection Factors for Chronic Diseases by Telephone Survey (Vigitel) and by the National Health Survey (PNS), in Rio Branco, Acre. Methods: Cross-sectional study, using sociodemographic, health and lifestyle variables from surveys conducted in 2019. Prevalences and 95% confidence intervals (95%CI) were described and percentage differences were calculated. Results: Of the 3,037 individuals evaluated, there was similarity in the prevalence, with difference in people with mixed race/skin color in Vigitel (60.3 ­ 95%CI 56.2;64.3) and PNS (70.8 ­ 95%CI 67.4;73.9). In the stratification by sex, percentage differences between the surveys were observed for obesity (male = 6.5%; female = 0.4%), smoking (male = 4.0%; female = -1.5%) and alcohol abuse (male = 6.9%; female = -2.5%), but with 95%CI overlapping. Conclusion: Estimates evaluated in both surveys were similar.

Objetivo: Comparar la prevalencia de enfermedades crónicas no transmisibles, consumo de alimentos ultraprocesados, alcohol y tabaco, según el Sistema de Vigilancia de Factores de Riesgo y Protección de Enfermedades Crónicas por Encuesta Telefónica (Vigitel) y por la Encuesta Nacional de Salud (PNS), en Rio Branco, Acre. Métodos: Estudio transversal, utilizando variables sociodemográficas, salud y estilo de vida de encuestas de 2019. Se describieron prevalencias e intervalos de confianza al 95% (IC95%) y se calcularon diferencias porcentuales. Resultados: Los 3.037 individuos evaluados, hubo similitud en la prevalencia, con diferencia en raza mixta/color de piel en Vigitel (60,3I ­ C95% 56,2;64.3) y SNP (70,8 ­ C95% 67,4;73,9). La estratificación por sexo, se observaron diferencias porcentuales entre las encuestas para obesidad (hombres 6,5%; mujeres 0,4%), tabaquismo (hombres = 4,0%; mujeres = -1,5%) y abuso de alcohol (hombres = 6,9%; mujeres = -2,5%), pero con IC95% superpuesto. Conclusión: Las encuestas arrojaron estimaciones similares.

Objetivo: Descrever, comparativamente, as prevalências de doenças crônicas não transmissíveis, consumo de alimentos ultraprocessados, álcool e tabaco, estimadas pelo Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (Vigitel) e pela Pesquisa Nacional de Saúde (PNS), Rio Branco, Acre, Brasil. Métodos: Estudo transversal, sobre dados sociodemográficos, de saúde e estilo de vida de inquéritos realizados em 2019. Foram descritas as prevalências e intervalos de confiança de 95% (IC95%), e calculadas as diferenças percentuais. Resultados: Dos 3.037 indivíduos avaliados, observou-se prevalências similares com diferença para pessoas de raça/cor da pele parda, entre Vigitel (60,3 ­ IC95% 56,2;64,3) e PNS (70,8 ­ IC95% 67,4;73,9). Na estratificação por sexo, diferenças percentuais entre os inquéritos foram observadas para obesidade (masculino = 6,5%; feminino = 0,4%), tabagismo (masculino = 4,0%; feminino = -1,5%) e consumo abusivo de álcool (masculino = 6,9%; feminino = -2,5%), embora com IC95% sobrepostos. Conclusão: As estimativas avaliadas em ambos inquéritos foram similares.

Food Insecurity and Associated Factors in Brazilian Undergraduates during the COVID-19 Pandemic.

Undergraduates may face challenges to assure food security, related to economic and mental distress, especially during the COVID-19 pandemic. This study aimed to assess food insecurity and its associated factors in undergraduates during the COVID-19 pandemic. An online cross-sectional study was conducted from August 2020 to February 2021 with 4775 undergraduates from all Brazilian regions. The questionnaire contained socio-economic variables, the validated Brazilian food insecurity scale, and the ESQUADA scale to assess diet quality. The median age of the students was 22.0 years, and 48.0% reported income decreasing with the pandemic. Food insecurity was present in 38.6% of the students, 4.5% with severe food insecurity and 7.7% moderate. Logistic regressions showed students with brown and black skin color/race presented the highest OR for food insecurity; both income and weight increase or reduction during the pandemic was also associated with a higher OR for food insecurity, and better diet quality was associated with decreased OR for food insecurity. Our study showed a considerable presence of food insecurity in undergraduates. Policy for this population must be directed to the most vulnerable: those with brown and black skin color/race, who changed income during the pandemic, and those presented with difficulties maintaining weight and with poor diet quality.

Fumonisin-containing diets decrease the metabolic activity of myenteric neurons in rats.

Fumonisins are naturally occurring mycotoxins that contaminate food for human and animal consumption. They have neurotoxic effects, but the mechanisms by which these toxins affect the nervous system are not fully known. In the present study, male Wistar rats were fed between 21 and 63 days of age with diets that contained fumonisins B1+B2 at 0, 1, and 4 mg/kg. The following variables were assessed: food consumption, growth, body weight gain, and blood parameters. Morphoquantitave analyses of the most metabolically active myenteric neurons were performed, detected by NADH-diaphorase activity. Nitrergic neurons were detected by NADPH-diaphorase activity. The fumonisin-containing diets did not significantly alter food consumption or the body or plasma parameters. These diets decreased the metabolic activity of jejunal myenteric neurons, reducing neuronal density of the most metabolic active neurons by 30.8% and the cell body area by 4.3%. The diets also decreased the cell body area of nitrergic neurons by 22.1%. The effects of fumonisin B1 on the respiratory metabolism of isolated mitochondria in the brain and liver were also assessed. A decrease in oxygen consumption up to a 29% in the brain and 38% in the liver was observed in mitochondrial isolates to which 50 µM fumonisin B1 was added. The decrease in respiratory activity that was triggered by exposure to fumonisins was related to the lower metabolic activity of myenteric neurons, which had a negative impact on neuroplasticity of the enteric nervous system.

Prevalência de consumo de alimentos ultraprocessados, álcool, tabaco e doenças crônicas não transmissíveis em Rio Branco, Acre, 2019: análise comparativa de dois inquéritos epidemiológicos / Prevalencia de consumo de alimentos ultraprocesados, alcohol, tabaco y enfermedades crónicas no transmisibles en Rio Branco, Acre, Brasil, 2019: análisis comparativo de dos encuestas epidemiológicas / Prevalence of ultra-processed food, alcohol and tobacco consumption and chronic non-communicable diseases in Rio Branco, capital city of the state of Acre, Brazil, 2019: comparative analysis of two epidemiological surveys

Objetivo: Descrever, comparativamente, as prevalências de doenças crônicas não transmissíveis, consumo de alimentos ultraprocessados, álcool e tabaco, estimadas pelo Sistema de Vigilância de Fatores de Risco e Proteção para Doenças Crônicas por Inquérito Telefônico (Vigitel) e pela Pesquisa Nacional de Saúde (PNS), em Rio Branco, Acre, Brasil. Métodos: Estudo transversal, sobre dados sociodemográficos, de saúde e estilo de vida de inquéritos realizados em 2019. Foram descritas as prevalências e intervalos de confiança de 95% (IC95%), e calculadas as diferenças percentuais. Resultados: Dos 3.037 indivíduos avaliados, observaram-se prevalências similares com diferença para pessoas de raça/cor da pele parda, entre Vigitel (60,3%; IC95% 56,2;64,3) e PNS (70,8%; IC95% 67,4;73,9). Na estratificação por sexo, diferenças percentuais entre os inquéritos foram observadas para obesidade (masculino= 6,5%; feminino= 0,4%), tabagismo (masculino= 4,0%; feminino= -1,5%) e consumo abusivo de álcool (masculino= 6,9%; feminino= -2,5%), embora com IC95% sobrepostos. Conclusão: As estimativas avaliadas em ambos os inquéritos foram similares.

Objetivo: Comparar la prevalencia de enfermedades crónicas no transmisibles, consumo de alimentos ultraprocesados, alcohol y tabaco, según el Sistema de Vigilancia de Factores de Riesgo y Protección de Enfermedades Crónicas por Encuesta Telefónica (Vigitel) y por la Encuesta Nacional de Salud (PNS), en Rio Branco, Acre. Métodos: Estudio transversal, utilizando variables sociodemográficas, salud y estilo de vida de encuestas de 2019. Se describieron prevalencias e intervalos de confianza al 95% (IC95%) y se calcularon diferencias porcentuales. Resultados: En los 3.037 individuos evaluados, hubo similitud en la prevalencia, con diferencia en raza/color de piel parda en Vigitel (60,3%; IC95% 56,2;64.3) y en PNS (70,8%; IC95% 67,4;73,9). En la estratificación por sexo, se observaron diferencias porcentuales entre las encuestas para obesidad (hombres= 6,5%; mujeres= 0,4%), tabaquismo (hombres= 4,0%; mujeres= -1,5%) y abuso de alcohol (hombres= 6,9%; mujeres= -2,5%), pero con IC95% superpuesto. Conclusión: Las encuestas arrojaron estimaciones similares.

Objective: To describe, in a comparative manner, the prevalence of chronic non-communicable diseases and ultra-processed food, alcohol and tobacco consumption, estimated by the Chronic Disease Risk and Protective Factors Surveillance Telephone Survey (Vigitel) and National Health Survey (PNS), in Rio Branco, capital city of the state of Acre, Brazil. Methods: This was a cross-sectional study on sociodemographic, health and lifestyle data from surveys conducted in 2019. Prevalence and 95% confidence intervals (95%CI) were described, and percentage difference was calculated. Results: Of the 3,037 individuals assessed, similar prevalence, with difference between Vigitel (60.3%; 95%CI 56.2;64.3) and PNS (70.8%; 95%CI 67.4;73.9) regarding people of Brown race/skin color was found. In the stratification by sex, it could be seen percentage difference between the surveys, regarding obesity (male= 6.5%; female= 0.4%), smoking (male= 4.0%; female= -1.5%) and alcohol abuse (male= 6.9%; female= -2.5%), although with overlapping 95%CI. Conclusion: The estimates assessed in both surveys were similar.

Breastfeeding patterns and factors associated with early weaning in the Western Amazon.

OBJECTIVE: To characterize breastfeeding patterns in the first six months of life and factors associated with early weaning in a birth-cohort in Rio Branco, state of Acre. METHODS: This is a prospective study with all babies born between April and June 2015. The mothers were interviewed soon after birth and between 6 and 15 months postpartum. At hospital discharge, breastfeeding was defined as exclusively (EBF), and breastfeeding (BF). In the follow-up, breastfeeding patterns were exclusive breastfeeding (EBF), predominant breastfeeding (PBF), and breastfeeding (BF). The interruption of breastfeeding in the first six months was classified as early weaning. The Kaplan Meier method (log-rank: 95%) was used to estimate the conditional probability of change in breastfeeding pattern, and early weaning risk. Crude and adjusted proportional Cox regression models, and their respective 95% confidence intervals (95%CI), were used to analyze the factors associated with early weaning. RESULTS: The study included 833 infants in EBF (95.4%) and BF (4.6%) at hospital discharge. During the first six months of life, the infant likely discharged in EBF remaining in EBF, becoming PBF, and BF, were respectively 16.4%, 32.3%, and 56.5%. The weaning likely at six months was statistically higher for infants discharged in BF (47.4%) when compared with those discharged in EBF (26%). Factors associated with early weaning were BF at hospital discharge (HR = 1.82; 95%CI 1.06-3.11), no mother cross-breastfeeding (HR = 2.50; 95%CI 1.59-3.94), pacifier use (HR = 6.23; 95%CI 4.52-8.60), less than six months of breastfeeding intention (HR = 1.93; 95%CI 1.25-2.98), lack of breastfeeding in the first hour of life (HR = 1.45; 95%CI 1.10-1.92), and pregnancy alcohol consumption (HR = 1.88; 95%CI 1.34-2.90). CONCLUSION: Compared to infants in EBF, those in BF at hospital discharge were more likely to wean. Public health efforts should prioritize EBF at hospital discharge, promote breastfeeding in the first hour of life, and prevent alcohol consumption risks during pregnancy, cross-breastfeeding and pacifier use.

Breastfeeding patterns and factors associated with early weaning in the Western Amazon / Padrões de amamentação e fatores associados ao desmame precoce na Amazônia ocidental

ABSTRACT OBJECTIVE: To characterize breastfeeding patterns in the first six months of life and factors associated with early weaning in a birth-cohort in Rio Branco, state of Acre. METHODS: This is a prospective study with all babies born between April and June 2015. The mothers were interviewed soon after birth and between 6 and 15 months postpartum. At hospital discharge, breastfeeding was defined as exclusively (EBF), and breastfeeding (BF). In the follow-up, breastfeeding patterns were exclusive breastfeeding (EBF), predominant breastfeeding (PBF), and breastfeeding (BF). The interruption of breastfeeding in the first six months was classified as early weaning. The Kaplan Meier method (log-rank: 95%) was used to estimate the conditional probability of change in breastfeeding pattern, and early weaning risk. Crude and adjusted proportional Cox regression models, and their respective 95% confidence intervals (95%CI), were used to analyze the factors associated with early weaning. RESULTS: The study included 833 infants in EBF (95.4%) and BF (4.6%) at hospital discharge. During the first six months of life, the infant likely discharged in EBF remaining in EBF, becoming PBF, and BF, were respectively 16.4%, 32.3%, and 56.5%. The weaning likely at six months was statistically higher for infants discharged in BF (47.4%) when compared with those discharged in EBF (26%). Factors associated with early weaning were BF at hospital discharge (HR = 1.82; 95%CI 1.06-3.11), no mother cross-breastfeeding (HR = 2.50; 95%CI 1.59-3.94), pacifier use (HR = 6.23; 95%CI 4.52-8.60), less than six months of breastfeeding intention (HR = 1.93; 95%CI 1.25-2.98), lack of breastfeeding in the first hour of life (HR = 1.45; 95%CI 1.10-1.92), and pregnancy alcohol consumption (HR = 1.88; 95%CI 1.34-2.90). CONCLUSION: Compared to infants in EBF, those in BF at hospital discharge were more likely to wean. Public health efforts should prioritize EBF at hospital discharge, promote breastfeeding in the first hour of life, and prevent alcohol consumption risks during pregnancy, cross-breastfeeding and pacifier use.

RESUMO OBJETIVO: Caracterizar os padrões de amamentação nos primeiros seis meses de vida e fatores associados ao desmame precoce numa coorte de nascidos vivos em Rio Branco, Acre. MÉTODOS: Estudo prospectivo com nascidos vivos entre abril e junho de 2015. As entrevistas com as mães ocorreram logo após o nascimento e entre 6 e 15 meses pós-parto. Na alta hospitalar, o aleitamento foi definido em exclusivo (AME) e materno (AM). No seguimento, os padrões de amamentação foram AME, aleitamento materno predominante (AMP) e AM. A interrupção da amamentação nos primeiros seis meses foi classificada como desmame precoce. Utilizou-se o método de Kaplan Meier (log-rank: 95%) para estimar a probabilidade condicional de mudança no padrão de amamentação e risco de desmame. Os fatores associados ao desmame e seus intervalos de confiança de 95% (IC95%) foram analisados pela regressão proporcional de Cox bruta e ajustada. RESULTADOS: Participaram do estudo 833 lactentes que na alta hospitalar estavam em AME (95,4%) e AM (4,6%). A probabilidade do lactente em AME na alta hospitalar permanecer em AME, ou se tornar AMP ou AM, aos seis meses, foi de 16,4%, 32,3% e 56,5% respectivamente. A probabilidade de desmame aos seis meses foi estaticamente maior para lactentes em AM na alta hospitalar (47,4%) em comparação com aqueles em AME (26%). Mostraram-se associados ao desmame precoce: o AM na alta hospitalar (HR = 1,82; IC95% 1,06-3,11), ausência de amamentação cruzada praticada pela mãe (HR = 2,50; IC95% 1,59-3,94), usar chupeta (HR = 6,23; IC95% 4,52-8,60), pretender amamentar por menos de seis meses (HR = 1,93; IC95% 1,25-2,98), não amamentar na primeira hora de vida (HR = 1,45; IC95% 1,10-1,92) e consumir álcool na gestação (HR = 1,88; IC95% 1,34-2,90). CONCLUSÃO: Comparados aos lactentes em AME, aqueles em AM, na alta hospitalar, apresentaram maior probabilidade de desmame. Esforços em saúde pública devem priorizar o AME na alta hospitalar, promover amamentação na primeira hora de vida e orientar sobre os riscos do consumo de álcool na gestação, amamentação cruzada e uso de chupeta.

Perfil calórico e higienicossanitário do leite pasteurizado pelo banco de leite humano do estado do Acre / Caloric and hygienicosanitary profile of the milk pasteurized by the human milk bank of the state of Acre

Este estudo teve por objetivo analisar o perfil calórico e higienicossanitário do leite humano pasteurizado pelo Banco de Leite Humano da Maternidade Barbara Heliodora, localizado no município de Rio Branco-AC. Trata-se de uma pesquisa descritiva e transversal realizada a partir de dados secundários do registro dos exames de teor calórico avaliados pelo crematócrito, e titulação de acidez pelo método de Dornic do leite humano coletado e processado pelo banco de leite humano referente ao período de janeiro a dezembro de 2014. Foram analisadas 499 amostras de leite humano, totalizando 146,39 litros de leite coletados. Deste leite humano pasteurizado 15% foi classificado como hipocalórico, 52% normocalórico e 33% hipercalórico. De acordo com o estágio de lactação, o leite maduro foi o leite com maior quantidade de doações. Em relação à acidez Dornic, encontraram-se resultados dentro da média de titulação aceitável, sendo os maiores valores encontrados na faixa de 4,1 a 7,9% (n=252). As perdas de leite materno representaram 18,34 litros, sendo as principais causas o prazo de validade expirado, quantidade insuficiente para o processamento, sujidade, frasco quebrado e doadora sem cadastro. As doações de leite humano são essenciais para a garantia do leite destinado às crianças que dele necessitam. Assim, o presente estudo concluiu que o leite é normocalórico e está próprio para o consumo, com relação ao alto teor calórico e baixa titulação acidez. É importante o registro dessas informações para que se intensifiquem os estudos nessa área e medidas que busquem melhorar as boas práticas de manipulação.

This study aimed to analyze the caloric and hygienic conditions of the pasteurized breast milk in a Breast Milk Bank in the maternity hospital Barbara Heliodora, in Rio Branco, Ac. This is a descriptive cross-sectional analyzes of secondary data survey of calorie tests by crematocrit, and titratable acidity of the Dornic method of human milk collected and processed by the Breast Milk Bank from January to December 2014. It was analyzed 499 samples of pasteurized breast milk or 146,39 liters. Of those, 15% was hypocaloric, 52% normalcaloric and 33% hypercaloric. The mature milk was the type of milk in more quantity of donations. The Dornic acidity found was between 4,1 to 7,9% (n=252), considered acceptable. A total 18,34 liters of breast milk wasted. The breast milk donations are essential guaranty of milk, designated to the ones in need. Therefore, the present study conclude that the milk is normocaloric and is suitable for consumption. It's important to record those informations so that more studies are performed in this area, besides measures and proceedings of good manipulation practices.

Infant mortality trend in the city of Rio Branco, AC, 1999 to 2015.

OBJECTIVE: Analyze the trend of infant mortality in Rio Branco, state of Acre, from 1999 to 2015. METHODS: An ecological observational study of a time series, in which data from deaths from the Information System on Mortality and Births of the Information System on Live Births were used. The annual percentage change was estimated using the Joinpoint software. RESULTS: The infant mortality rate decreased from 26.99 in 1999 to 14.50 in 2015 per 1,000 live births, with an annual percentage change of -4.37 (95%CI -5.4- -3.4). When stratified by age components, the neonatal period presented an annual percentage change of -4.73 (95%CI -5.7- -3.7), and the post-neonatal period was -3.7 (95%CI -5.4- -2.0). Avoidability, avoidable causes and poorly defined causes showed a downward trend throughout the period and causes not clearly preventable showed an upward trend until 2008. The group of causes that contributed most to the infant deaths during the period studied was perinatal diseases, followed by malformations, infectious and parasitic diseases, and respiratory diseases. CONCLUSIONS: Despite the decreasing trend in infant mortality rates in the capital compared to developed countries, it is relatively high.

Infant mortality trend in the city of Rio Branco, AC, 1999 to 2015 / Tendência da mortalidade infantil no município de Rio Branco, AC, 1999 a 2015

ABSTRACT OBJECTIVE Analyze the trend of infant mortality in Rio Branco, state of Acre, from 1999 to 2015. METHODS An ecological observational study of a time series, in which data from deaths from the Information System on Mortality and Births of the Information System on Live Births were used. The annual percentage change was estimated using the Joinpoint software. RESULTS The infant mortality rate decreased from 26.99 in 1999 to 14.50 in 2015 per 1,000 live births, with an annual percentage change of -4.37 (95%CI -5.4- -3.4). When stratified by age components, the neonatal period presented an annual percentage change of -4.73 (95%CI -5.7- -3.7), and the post-neonatal period was -3.7 (95%CI -5.4- -2.0). Avoidability, avoidable causes and poorly defined causes showed a downward trend throughout the period and causes not clearly preventable showed an upward trend until 2008. The group of causes that contributed most to the infant deaths during the period studied was perinatal diseases, followed by malformations, infectious and parasitic diseases, and respiratory diseases. CONCLUSIONS Despite the decreasing trend in infant mortality rates in the capital compared to developed countries, it is relatively high.

RESUMO OBJETIVO Analisar a tendência da mortalidade infantil em Rio Branco, AC, de 1999 a 2015. MÉTODOS Estudo observacional ecológico de série temporal, em que foram utilizados dados de óbitos do Sistema de Informações sobre Mortalidade e Nascimentos do Sistema de Informações sobre Nascidos Vivos. Estimou-se a variação percentual anual por meio do software Joinpoint. RESULTADOS A taxa de mortalidade infantil reduziu de 26,99, em 1999, para 14,50, em 2015, por 1.000 nascidos vivos, com variação percentual anual de -4,37 (IC95% -5,4- -3,4). Quando estratificada por componentes etários, o neonatal apresentou variação percentual anual de -4,73 (IC95% -5,7- -3,7), e o pós-neonatal de -3,7 (IC95% -5,4- -2,0). A evitabilidade, as causas evitáveis e as causas mal definidas apresentaram tendência descendente em todo o período e as causas não claramente evitáveis apresentaram tendência ascendente até 2008. O grupo de causas que mais contribuiu para os óbitos infantis no período estudado foi o das afecções perinatais, seguido pelo das malformações, das doenças infecciosas e parasitárias, e do grupo das doenças respiratórias. CONCLUSÕES Apesar da tendência decrescente da taxa de mortalidade infantil na capital, quando comparada à de países desenvolvidos, mostra-se relativamente elevada.

Conhecimento de merendeiros sobre segurança dos alimentos, em pré-escolas atendidas pelo PNAE, no município de Rio Branco - AC / Knowledge of food security workers in pre-schools attended by the PNAE in the municipality of Rio Branco - AC

Estudo descritivo transversal foi realizado nas escolas de ensino infantil de Rio Branco-Acre. Utilizou-se um instrumento semiestruturado em quatro blocos com o objetivo de colher informações demográficas e avaliar o conhecimento, atitudes e práticas dos manipuladores de alimentos. Os resultados demonstraram que 93,3% dos manipuladores eram do sexo feminino, com idade superior a 31anos (63,3%) e concursados (90,0%). Em relação ao tempo de exercício na função 66,7% estavam há menos de um ano na função. Observou- -se que o escore de conhecimento apresentou resultados abaixo do satisfatório (59,12%), as atitudes foram consideradas satisfatórias (84,75% de acertos). O escore de práticas apresentou 70,17% de acertos. Foi possível concluir que, mesmo apresentando pouco conhecimento, os merendeiros demonstram atitudes e práticas com resultados satisfatórios. Os manipuladores parecem ter suas atitudes guiadas por um conhecimento empírico adquirido por meio da experiência.

Pesticide use and cholinesterase inhibition in small-scale agricultural workers in southern Brazil

A controlled cross-sectional study of family growers of fruit and vegetables was conducted between October 2009 and October 2010 to characterize the use of pesticides, establish the socio-demographic profile, and analyze cholinesterase activity in small-scale agricultural workers in Southern Brazil. Data was collected for 173 workers and 179 controls. A structured questionnaire was applied collecting socio-demographic information and determining knowledge and work practices in relation to pesticide use. The benchmarks for total cholinesterase (ChEs) and butyrylcholinesterase (BuChE) were obtained from the average enzymatic activity of the occupationally unexposed group (control). The mean age of the exposed population was 40.0 ± 11.2 years. The symptoms differed significantly (p<0.05) between the exposed and unexposed populations. Forty (23.1%) workers showed symptoms associated with exposure to pesticides. The average value of enzymatic activity in the occupationally unexposed group for ChEs was 6.3 μmol/mL/min among males and 5.6 μmol/mL/min among females while for BuChE was 2.4 μmol/mL/min among males and 2.0 μmol/mL/min among females. Eight (4.6%) workers had high inhibition (>30%) of ChEs activity, whereas no workers showed high inhibition (>50%) of BuChE. Potential factors involved include gender, education, pesticide orientation, exposure, and hygiene measures.

Realizou-se um estudo transversal controlado, com hortifruticultores, durante o período de outubro de 2009 a outubro de 2010, a fim de caracterizar o uso de praguicidas, estabelecer o perfil sócio demográfico e analisar a atividade das colinesterases em trabalhadores rurais do sul do Brasil. Os dados foram obtidos de 173 trabalhadores e 179 controles. Um formulário estruturado foi aplicado obtendo informações sócio demográficas, conhecimento e práticas de trabalho relacionadas com o uso de praguicidas. Os valores de referência para colinesterases totais (ChEs) e butirilcolinesterase (BuChE) foram obtidos a partir da média da atividade enzimática do grupo controle. A idade média da população exposta foi de 40,0±11,2 anos. Os sinais/sintomas foram significativamente diferentes (p<0,05) entre a população exposta e não exposta. Quarenta trabalhadores (23,1%) apresentaram sinais/sintomas relacionados com a exposição aos praguicidas. O valor médio do grupo controle foi de 6,3 μmol/mL/min para o gênero masculino e 5,6 μmol/mL/min para o gênero feminino na ChEs; 2,4 μmol/mL/min para o gênero masculino e 2,0 μmol/mL/min para o gênero feminino na BuChE. Do total de trabalhadores (n=173), 08 (4,6%) apresentaram inibição elevada (>30%) das atividades das ChEs, e para BuChE nenhum trabalhador apresentou alta inibição (>50%). Dentre os fatores que poderiam estar envolvidos destacam-se o gênero, escolaridade, orientação para trabalhar com praguicidas, exposição e medidas de higiene.